Project title: Receptor trafficking pathways in breast cancer
Prof Johanna Ivaska, University Turku, Turku Centre for Biotechnology
Three-year fixed-term contract for a postdoctoral researcher - negotiable start date April 1st 2017
The Cell Adhesion and Cancer group is a vibrant, international multidisciplinary team working towards a comprehensive understanding of how cell survival and motility facilitate tumour development and metastatic spread in human cancer. Specifically, we focus on identifying novel elements that regulate the function of integrins and receptor tyrosine kinases (RTKs) – two endosomally trafficking receptor systems that demonstrate extensive cross-talk in transformed cells, and that are implicated in cancer progression and resistance to drug therapy. We are particularly interested in the basic molecular mechanisms of cell migration, adhesion and receptor traffic in relevant cancer models and couple these investigations to the analysis of clinical therapy-resistant breast cancer samples. Ultimately, our studies aim to provide insights into both improving existing clinical regimens and in identifying novels targets for therapeutic intervention.
We are looking for a highly motivated post-doctoral fellow to investigate novel trafficking pathways, identified in our laboratory in large-scale unbiased screens, in cancer progression. Applicants will have successfully completed a PhD in a field relevant to the molecular and cellular biology of cancer and/or membrane trafficking and published at least one peer-reviewed article. Microscopy skills, experience in mammalian cell culture and molecular biology as well as knowledge of membrane trafficking would also be an advantage.
Turku is the oldest city in Finland (est. 1229) with nearly 200 000 inhabitants, two universities and over 35 000 students, located on the south-west coast on Finland 150 km west of Helsinki. The University of Turku is an active academic community of 25 000 students and staff members – a truly international research university. Accordingly, the work language is English and there is no need or requirement to learn Finnish. Furthermore, Finland is considered to have a high quality of life, education, gender equality, transparency and safety where the majority of the population speaks English as a second language.
The salary is in accordance with the universities salary system (for teaching and research personnel) level 5 where the work specific salary component is 2865.30 €/month. In addition, there is a share increase based on the personal performance, which is, at most, 46.3 % of the base salary. There is a trial period of four months.
For more information on the research group, recent publications and ongoing projects please visit www.ivaskalab.com and the Turku Centre for Biotechnology at http://www.btk.fi/home/main/
For informal enquiries please email Prof Ivaska at firstname.lastname@example.org. Enquiries concerning the application procedure may be directed to coordinator Ulla Karhunen, email email@example.com.
The applications for the position must be submitted latest on February 14th 2017 using an electronic system. A link to the electronic application system can be found on top of the position advertisement from the following link: http://www.utu.fi/careers. Please include CV, list of publications and contact information of two referees in your application.